What Is Micronized Progesterone?

Micronized bioidentical progesterone is a prescription capsule used to restore declining progesterone levels in peri- and post-menopausal women. It is chemically identical to the progesterone your body naturally produces. Micronization improves absorption and bioavailability, making it more effectively utilized by the body.

What Is Progesterone and Why Does It Decline?

Progesterone is a key hormone for women's health, supporting menstrual regulation, sleep, mood, uterine health, bone health, cardiovascular function, and cognitive performance. Like estrogen, progesterone levels decline with age and drop significantly during perimenopause and menopause.

Key Benefits of Micronized Progesterone

• Improves sleep quality and supports relaxation (via GABA effects)
• Promotes stable mood and reduces anxiety and irritability
• Balances estrogen and protects the uterine lining
• Reduces hot flashes and night sweats
• Supports bone, brain, and cardiovascular health
• Helps regulate cycles and reduce heavy or irregular bleeding during perimenopause

Who Typically Needs Progesterone?

Progesterone is typically required for uterine protection when used alongside systemic estrogen therapy. Women without a uterus generally do not need progesterone.

Many patients notice improvements in sleep and mood within weeks of starting treatment.

Bioidentical vs. Synthetic Progesterone

AgelessRx prescribes only bioidentical progesterone, not synthetic alternatives (progestins). Only synthetic progesterone has been associated with a higher risk of certain conditions. Bioidentical progesterone may be associated with a lower risk profile when combined with estrogen therapy.

How Long Will I Be on Progesterone?

There is no set limit on the duration of bioidentical hormone replacement therapy. Benefits are maintained while you are actively on treatment. Your provider will evaluate your needs over time.

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